EntityRisk integrates globally renowned health economics and policy expertise with PROVEN™, our advanced modeling software, to predict health outcomes, identify maximum value-based pricing, and substantiate evidence-generation investments, allowing you to better establish and defend product value.
PROVEN™ uses the latest advances in machine learning and Bayesian methods to make health economic modeling more robust, transparent, and flexible.
With PROVEN™, you can model multiple advanced value frameworks simultaneously, include novel value elements, quantify the impact of each piece of evidence, optimize TPPs, and run real-time scenarios.
Why EntityRisk
The pressure surrounding pricing and clinical investments continues to climb, and the current environment demands better, faster, and more innovative analytics.
EntityRisk combines world-class academic expertise in health economics and policy with the latest HEOR methodologies into a customizable, transparent software platform called PROVEN™.
PROVEN™ delivers durable disease models, pricing validation, and evidence quantification, all within a dynamic, centralized system designed to evolve with your product and the market.
Build and Pressure Test Your Best Value Story
PROVEN™ simultaneously runs multiple economic and clinical frameworks and incorporates novel value elements, positioning you at the forefront of the evolving value assessment landscape.
Predict Real-World Outcomes, Risk, Price, and Commercial Revenue
PROVEN™ creates robust disease models and accurately predicts outcomes, price and revenue, even with small datasets or TPPs, a critical capability for rare and orphan diseases and early-pipeline assets.
Quantify the Commercial Impact of Evidence
PROVEN™ applies advanced machine-learning and game theory techniques to directly link and quantify the individual impact of each aspect of a product profile on an outcome of interest such as value so you can focus evidence-generation efforts for maximum return.
Adapt Across Products and Geographies
PROVEN™ runs off a core unified and parameterized software-based disease model so you can expedite local adaptations while maintaining consistency with standardized global models and avoiding errors and “model drift.”
Run Advanced Disease Model Simulations
PROVEN™ contains the code for any type of disease model and advanced scientific methods from a variety of domains along with audit reports and 1,300 automated quality checks that consistently identify errors, ensuring highly accurate, defensible, and transparent analytics and insights.
Seamlessly Update Models with New Data
PROVEN™ merges and analyzes all available data, including Randomized Controlled Trial data and Real-World data, into a single, unified model and allows for easy model updates at the push of a button.
EntityRisk’s
PROVEN™ Platform
PROVEN™ provides advanced forecasting tools for price, outcomes, value, and evidence generation planning. It was built on the premise that a robust disease progression simulation is key to successful product development and commercialization. PROVEN’s Python core and modular design can handle any conceivable disease model quickly and accurately.
OutcomesML™
Predict the distribution of real-world health outcomes for pipeline or marketed products of interest from clinical trial data (including surrogate end points and biomarkers), real world data, and/or TPPs.
ValueML™
Simulate a full array of justifiable “value-based” prices, budget impact, and cost-effectiveness outcomes using multiple value assessment frameworks simultaneously to support pricing strategies, payer negotiations, and HTA submissions.
EvidenceML™
Directly link evidence to impact and quantify the elasticity and risk surrounding product or population characteristics to prioritize evidence investments, optimize trial design, and establish and update TPPs and product forecasts.
PriceML™
Predict the likely distribution of real-world WAC and net prices for any given target product profile.
CommercialML™
Forecast long-term revenues and downside risks over a product’s lifecycle for a range of pricing and contracting strategies and efficacy and marketplace competition scenarios.
Value, Pricing,
and Evidence Planning
...Evolved
Thought Leadership
The latest news and insights from across the industry
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- by : Gayle Goldner
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- by : EntityRisk
- Published on
- by : EntityRisk
